Advancing Anthrax Response Capabilities

This week, EPA is hosting the 7th annual international conference on decontamination research and development in Research Triangle Park, North Carolina.

To help spread the word about the conference, which brings top experts from around the world to advance collaboration and share information on cleaning up contamination—especially chemical, biological, and radiological agents—we are posting “EPA Science Matters” newsletter feature stories.

Advancing Anthrax Response Capabilities
EPA researchers developed an open-access protocol for anthrax detection and informing response activities

Scanning electron micrograph (SEM) depicted spores from the Sterne strain of Bacillus anthracis bacteria. Image courtesy of Centers for Disease Control and Prevention.

Scanning electron micrograph (SEM) depicted spores from the Sterne strain of Bacillus anthracis bacteria. Image courtesy of Centers for Disease Control and Prevention.

During and following an anthrax attack, emergency responders and clean-up officials will depend on many different laboratories to process large quantities of various kinds of samples to determine the nature and extent of contamination.  And then, after initial clean-up efforts have been completed, multiple “clearance” samples would need to be tested to evaluate whether anthrax-causing Bacillus anthracis spores were adequately reduced.

EPA researchers have combined many of the analytical procedures the Agency’s Environmental Response Laboratory Network (ERLN)  would need to perform into a single, “open-access” protocol, the Protocol for Detection of B. anthracis in Environmental Samples during the Remediation Phase of an Anthrax Event (2012).   “Open-access” means that laboratories across the nation have access to a consistent set of directions and to the key components of the analysis.  The essential additives, developed by Agency researchers, are DNA probes for Bacillus anthracis that laboratories need to conduct rapid analysis.

The ERLN is a nationwide network of federal, state, local and commercial environmental laboratories (including sub-network for water samples, the Water Laboratory Alliance) charged with analyzing chemical, biological and radiological contamination following a terrorist attack.

“With the availability of this open access Protocol, EPA and its partners will be able to analyze a large number of environmental samples to detect Bacillus anthracis quickly and accurately during any incident.  The Ba Protocol would also enable laboratory analysts to compare lab results from one to another,” explains Sanjiv Shah, Ph.D. senior EPA microbiologist.

Reducing the time it takes for labs to provide officials with the data they will need to guide clean-up efforts and advise occupants on when they can start to re-visit or re-occupy formerly contaminated facilities is another expected impact of the Protocol.

“The availability of this new EPA Protocol will improve the nation’s ability to protect our health and environment and ease the hard work of recovery following an anthrax incident,” says EPA’s Acting Associate Administrator for Homeland Security, Juan Reyes.


Editor's Note: The views expressed here are intended to explain EPA policy. They do not change anyone's rights or obligations. You may share this post. However, please do not change the title or the content, or remove EPA’s identity as the author. If you do make substantive changes, please do not attribute the edited title or content to EPA or the author.

EPA's official web site is Some links on this page may redirect users from the EPA website to specific content on a non-EPA, third-party site. In doing so, EPA is directing you only to the specific content referenced at the time of publication, not to any other content that may appear on the same webpage or elsewhere on the third-party site, or be added at a later date.

EPA is providing this link for informational purposes only. EPA cannot attest to the accuracy of non-EPA information provided by any third-party sites or any other linked site. EPA does not endorse any non-government websites, companies, internet applications or any policies or information expressed therein.